Four changes for Scotland: WP Nel comes into the front row, with Jamie Ritchie returning at blindside flanker. Sean Maitland is fit again after an achilles tendon injury, and starts on the wing, with Gloucester’s Chris Harris making his first start of the tournament at outside centre.
Three tweaks to the starting lineup, meanwhile, for Ireland: Keith Earls comes in on the wing, with Cian Healy and Rob Herring starting in the front row. CJ Stander, starting at No 8, wins his 50th cap. Conor Murray is fit again but Jamison Gibson-Park is preferred to start at scrum-half alongside Johnny Sexton at No 10.
Scotland: 15. Stuart Hogg, 14. Sean Maitland, 13. Chris Harris, 12. Sam Johnson, 11. Duhan van der Merwe, 10. Finn Russell, 9. Ali Price, 1. Rory Sutherland, 2. George Turner, 3. WP Nel, 4. Scott Cummings, 5. Jonny Gray, 6. Jamie Ritchie, 7. Hamish Watson, 8. Matt Fagerson
Replacements: 16. David Cherry, 17. Jamie Bhatti, 18. Simon Berghan, 19. Grant Gilchrist, 20. Nick Haining, 21. Scott Steele, 22. Huw Jones, 23. Darcy Graham
Ireland: 15. Hugo Keenan, 14. Keith Earls, 13. Garry Ringrose, 12. Robbie Henshaw, 11. James Lowe, 10. Johnny Sexton, 9. Jamison Gibson-Park, 1. Cian Healy, 2. Rob Herring, 3. Tadhg Furlong, 4. Iain Henderson, 5. James Ryan, 6. Tadhg Beirne, 7. Will Connors, 8. CJ Stander
Replacements: 16. Ronan Kelleher, 17. Dave Kilcoyne, 18. Andrew Porter, 19. Ryan Baird, 20. Jack Conan, 21. Conor Murray, 22. Billy Burns, 23. Jordan Larmour