A 2018 photo of Amanda Adams’ research group in the Department of Veterinary Science includes (Left to right): Suzanne Schindler, Alex Bertke, Ashton Miller, John Allen, Stephanie Reedy, Melissa Siard, Mason Mulholland, Amanda Adams, Chip Stamper, Sarah Elzinga, Alessandra Campana, Sarah Sivinski. The photo was taken at the horse facilities at UK’s C. Oran Little Research Center. Photo by Steve Patton, UK agricultural communications.
Horses aged 15 and over make up between 20 to 30 percent of the United States equine population. An important milestone will be reached this year in the quest to learn more about this population. October marks the one-year anniversary of Amanda Adams, associate professor at the University of Kentucky Gluck Equine Research Center specializing in aged horse research, becoming the first MARS Equestrian Fellow. This fellowship supports her work to improve not only how the industry cares for senior horses but also how veterinarians can better diagnose the conditions and diseases that affect them.
According to Linda Mars, gaining a better understanding of how nutritional and management requirements change with age and activity will help the industry provide the best possible care to horses and ponies throughout their lives.
As horses age, they face an increased risk for some common conditions and diseases. One of those, pituitary pars intermedia dysfunction, develops in approximately 20 percent of senior horses. Another condition, equine metabolic syndrome, is associated with insulin dysregulation and often obesity. This can occur in all aged animals but may have additional adverse consequences in the older horse. Both are associated with the development of laminitis, a very painful and debilitating condition of the hoof that is often life ending.
These are just two of the key problems that Adams’ team has been able to work on with MARS Equestrian support. Her team has established and maintains a unique herd of nearly 80 aged, obese and metabolic syndrome horses. The herd is the only one of its kind in the U.S., and it provides unique opportunities to study geriatric and endocrine diseases in horses.
According to Adams, most of what her team knows and what they are learning about aging and endocrine diseases in this population of special needs horses wouldn’t be possible without access to this research herd.
“In a short period of time, we have made major breakthroughs in gaining a better understanding of how to nutritionally manage horses suffering from insulin dysregulation, specifically in equine metabolic syndrome horses. We are also learning that the season has a profound influence on the metabolic responses of these diseased horses, which will help shed light on why these horses may develop laminitis at certain times of the year,” said Adams, a faculty member of the UK College of Agriculture, Food and Environment. “Over the last year, we have also been working to define sarcopenia (an age-related loss of skeletal muscle mass and strength) in aged horses and how specific diet and exercise routines may reverse or improve that muscle loss. Furthermore, we are studying what effect exercise has on the inflammation-aging response in aged horses.”
While the progress is promising, Adams said that more work is needed. In addition to learning how to better manage these horses, there is a need at the basic scientific level to understand how the aging process affects the horse’s immunity, metabolic status and nutritional needs.
“The many problems we face with the aging horse are important given the growing senior horse population,” said Pat Harris, Director of Science, MARS Horsecare. “Thus, it is critical that we continue these efforts to advance the field and improve our knowledge in senior horse care,” “ultimately creating a better world for horses” added Bridgett McIntosh, Director of MARS Equestrian.
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