Argentine Diego Schwartzman kicks things off on Centre Court against Richard Gasquet and that is followed by Venus Williams vs Donna Vekic while in the first match on Grandstand, top seed Ashleigh Barty plays Anett Kontaveit.
Seven-time champion Roger Federer finishes off the day session against Andrey Rublev in their first-ever meeting.
Elsewhere, defending champion Novak Djokovic opens the night session on Centre then Elina Svitolina takes on Sofia Kenin.
And Andy Murray continues his return from hip surgery in the doubles with Feliciano Lopez against American duo Ryan Harrison and Jack Sock.
CINCINNATI MASTERS ORDER OF PLAY – AUGUST 15
CENTER COURT – 4PM BST
Diego SCHWARTZMAN (ARG) vs [PR] Richard GASQUET (FRA)
Venus WILLIAMS (USA) vs Donna VEKIC (CRO)
Roger FEDERER (SUI) [3] vs [Q] Andrey RUBLEV (RUS)
Not before 12am
Novak DJOKOVIC (SRB) [1] vs [Q] Pablo CARRENO BUSTA (ESP)
Elina SVITOLINA (UKR) [7] vs Sofia KENIN (USA)
GRANDSTAND – 4PM
Ashleigh BARTY (AUS) [1] vs Anett KONTAVEIT (EST)
Daniil MEDVEDEV (RUS) [9] vs Jan-Lennard STRUFF (GER)
[Q] Miomir KECMANOVIC (SRB) vs Roberto BAUTISTA AGUT (ESP) [11]
Lucas POUILLE (FRA) vs Karen KHACHANOV (RUS) [8]
Madison KEYS (USA) [16] vs Simona HALEP (ROU) [4]
STADIUM 3 – 4PM
[Q] Yoshihito NISHIOKA (JPN) vs Alex DE MINAUR (AUS)
David GOFFIN (BEL) [16] vs Adrian MANNARINO (FRA)
Karolina PLISKOVA (CZE) [3] vs [Q] Rebecca PETERSON (SWE)
[WC] Svetlana KUZNETSOVA (RUS) vs Sloane STEPHENS (USA) [8]
[WC] Ryan HARRISON (USA) & Jack SOCK (USA) vs Feliciano LOPEZ (ESP) & [PR] Andy MURRAY (GBR)
COURT 4 – 5PM
Cristian GARIN (CHI) & Benoit PAIRE (FRA) vs Lukasz KUBOT (POL) & Marcelo MELO (BRA) [2]
Diego SCHWARTZMAN (ARG) & Horacio ZEBALLOS (ARG) vs Henri KONTINEN (FIN) & John PEERS (AUS) [7]
Marcelo DEMOLINER (BRA) & Daniil MEDVEDEV (RUS) vs Mate PAVIC (CRO) & Bruno SOARES (BRA) [6]
Juan Sebastian CABAL (COL) & Robert FARAH (COL) [1] vs [Alt] Rohan BOPANNA (IND) & Denis SHAPOVALOV (CAN)
COURT 10 – 4PM
Aryna SABALENKA (BLR) [9] vs Maria SAKKARI (GRE)
Anna-Lena GROENEFELD (GER) & Demi SCHUURS (NED) [5] vs [WC] Catherine MCNALLY (USA) & Alison RISKE (USA)
Su-Wei HSIEH (TPE) vs Naomi OSAKA (JPN) [2]
Bethanie MATTEK-SANDS (USA) & CoCo VANDEWEGHE (USA) vs Alizé CORNET (FRA) & Kristina MLADENOVIC (FRA)
Su-Wei HSIEH (TPE) & Barbora STRYCOVA (CZE) [1] vs Lucie HRADECKA (CZE) & Andreja KLEPAC (SLO) [8]
COURT 7 – 8PM
Barbora KREJCIKOVA (CZE) & Katerina SINIAKOVA (CZE) [3] vs [WC] Karolina PLISKOVA (CZE) & Kristyna PLISKOVA (CZE)
