Cardinals at Browns spread, odds, picks and trends: Expert predictions for NFL Week 6 game

Cleveland did just about everything right offensively last week. Nick Chubb and Kareem Hunt took advantage of a bad run defense for 222 yards, Baker Mayfield threw for another 301 yards, 42 points were scored, and there wasn’t a single turnover. And the Browns still lost. It was just an unfortunate situation for Cleveland where the Chargers could match the Browns offensively and took advantage of their final possession. So Cleveland drops to 3-2, but don’t let that record fool you. The two losses are by 10 total points. Cleveland remains one of the more formidable teams in the AFC, and it’ll look to prove it against the unbeaten Cardinals. Oddsmakers like the Browns at home as they opened as three-point favorites.

Arizona is the league’s last undefeated team, and this Sunday will be its third game as an underdog. It won outright the first two times. Last week was the first instance this year that the Cardinals looked vulnerable. Their 304 yards were a season-worst by more than 100 yards as the run game was non-existent. However, a shorthanded Arizona defense stepped up to hold San Francisco to 10 points. Holding off the Rams at the top of the NFC West won’t be easy, but that was the type of win that should give the Cardinals confidence they can do so.

Odds, Over/Under, Moneyline

Team Spread Total Moneyline





All odds from BetMGM. Odds updated at 10 a.m. Wednesday. Click here for live odds.

Storylines for Cardinals-Browns

Arizona Cardinals news

Cleveland Browns news

Expert picks

Writer Straight Up Pick

Tashan Reed

Nick Kosmider

Jay Morrison

Mark Kaboly

Michael-Shawn Duger

Chris Burke

Ben Standig

Katherine Terrell

Ted Nguyen

(Photo of Nick Chubb: Patrick Martinez / Getty Images; The Athletic may receive an affiliate commission if you open an account with BetMGM through links contained in the above article.)

Get all-access to exclusive stories.

Subscribe to The Athletic for ad-free, in-depth coverage of your favorite players, teams, leagues and clubs. Try a week on us.



Leave a Reply

This website uses cookies. By continuing to use this site, you accept our use of cookies.