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Bills at Titans spread, odds, picks and trends: Expert predictions for NFL Week 6 game on Monday Night Football


Of the three 4-1 teams in the AFC, Buffalo has by far been the most impressive. After dropping their opener, the Bills have never looked back, averaging 420.3 yards and 39 points per game. Last week, the Bills crushed Kansas City 38-20. Josh Allen gained 374 scrimmage yards and scored four total touchdowns while the defense forced four turnovers. Allen is currently the betting favorite for MVP and has the league’s top-scoring defense too. Buffalo opened as 4.5-point road favorites at Tennessee this week. The Bills are 4-1 against the spread.

The Titans have their work cut out for them this week. Sure, they rebounded from a loss to the Jets. But it was an uninspiring performance against Jacksonville. Tennessee was outgained by the Jaguars and gave up seven yards per play. That’s not a formula for success against Buffalo. Neither is running Derrick Henry 30 times.

Odds, Over/Under, Moneyline

Team Spread Total Moneyline

-5.5

54

-250

+200

All odds from BetMGM. Odds updated at 9:15 a.m. Sunday. Click here for live odds.

Betting Trends

  • Line moved from Bills -4.5 to Bills -5.5
  • 89 percent of money bet on Bills on spread
  • 91 percent of money bet on Bills’ ML

Click here to learn more about The Athletic’s FREE betting contest with BetPrep.

  • The Over is 24-6-1 in Titans games in their last 31 games
  • The Bills are 10-0 ATS after a win in their last 10 games
  • The Bills are 10-0 ATS after they covered in their last 10 games
  • The Bills are 6-0 ATS on the road in their last 6 games
  • The Bills are 6-0 ATS against a top 10 defense in their last 6 games
  • The Bills are 5-0 on the road in their last 5 games
  • The Bills are 5-0 ATS against a team with a winning record in their last 5 games
  • The Bills are 12-1 ATS in their last 13 games
  • The Bills are 7-1 ATS as favorites in their last 8 games

Storylines for Bills-Titans

Buffalo Bills news

The Bills head into this Monday Night Football game with both the NFL’s top scoring offense and top defense. Buffalo is scoring 34.4 points per game behind the efficient offensive play of quarterback Josh Allen, who is coming off a 315-yard, three-touchdown performance that saw him post a season-high passer rating of 139.1. The Bills are allowing just 251 yards and 12.8 points per game, the fewest in the NFL, and boast the best turnover margin (plus-11). Safety Micah Hyde has logged an interception in his last three games and rookie defensive end Gregory Rousseau, who leads the Bills with three sacks, is the only first-year player with a sack and an interception in a single game this season.

Tennessee Titans news

Henry had his fifth career game with at least 100 yards and three touchdowns and currently has the longest active streak of 100-yard rushing games with four. He entered Week 6 leading the NFL with 640 rushing yards and seven total touchdowns. Tennessee will need big plays from its defense. Harold Landry had two sacks in Week 5 and safety Kevin Byard is coming off a game where he tallied 10 tackles, two pass deflections, an interception and a fumble recovery.

Expert picks

Writer Straight Up Pick

Tashan Reed

Nick Kosmider

Jay Morrison

Mark Kaboly

Michael-Shawn Dugar

Chris Burke

Ben Standig

Katherine Terrell

Ted Nguyen

More NFL Expert Picks

(Photo of Josh Allen: Scott Winters / Getty Images; The Athletic may receive an affiliate commission if you open an account with BetMGM through links contained in the above article.)

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